Longevity

What it is. Acetyl-L-Carnitine is an acetylated form of L-carnitine that crosses the blood-brain barrier more efficiently than standard carnitine. It plays a dual role in energy metabolism and neuroprotection.

What it does. ALCAR shuttles fatty acids into mitochondria for energy production and provides acetyl groups for acetylcholine synthesis. It supports mitochondrial function, cognitive performance, and cellular energy metabolism.

Why we include it. ALCAR addresses two hallmarks of aging simultaneously — mitochondrial decline and reduced acetylcholine availability — making it one of the most versatile longevity compounds.

What it is. Alpha Lipoic Acid is unique among antioxidants in being both water-soluble and fat-soluble — meaning it can neutralize free radicals in virtually every compartment of the cell, including mitochondria.

What it does. ALA functions as a cofactor for mitochondrial energy enzymes and regenerates other antioxidants including vitamins C and E and glutathione. It also supports healthy glucose metabolism and reduces oxidative stress.

Why we include it. ALA's universal antioxidant activity and mitochondrial support address the oxidative damage that accumulates with age — protecting cellular machinery at multiple levels.

What it is. Astragalus is a traditional Chinese herb that has gained modern attention for its potential effects on telomere biology. It contains cycloastragenol, a compound studied for telomerase activation.

What it does. Astragalus supports immune function and has been studied for its potential to activate telomerase — the enzyme that maintains telomere length. Telomere shortening is a hallmark of cellular aging.

Why we include it. Astragalus addresses aging at the chromosomal level — supporting the telomere maintenance mechanisms that influence cellular lifespan and replicative capacity.

What it is. CoQ10 is essential for mitochondrial electron transport — the process that produces 95% of the body's cellular energy. Endogenous production declines significantly with age.

What it does. CoQ10 shuttles electrons in the mitochondrial respiratory chain and acts as a potent lipid-soluble antioxidant. It protects mitochondrial membranes from oxidative damage while supporting ATP synthesis.

Why we include it. CoQ10 directly addresses the age-related decline in mitochondrial function — restoring a critical cofactor that becomes depleted as we age.

What it is. EGCG is the most abundant and bioactive polyphenol in green tea. It has been extensively studied for its antioxidant, anti-inflammatory, and potential senolytic properties.

What it does. EGCG activates AMPK (the cellular energy sensor), inhibits mTOR (supporting autophagy), and has demonstrated senolytic activity — helping clear damaged senescent cells that accumulate with age.

Why we include it. EGCG addresses multiple longevity pathways — metabolic sensing, autophagy activation, and senescent cell clearance — making it one of the most comprehensive single compounds for healthy aging.

What it is. Glutathione is the body's most abundant endogenous antioxidant — present in every cell. The S-Acetyl form is stabilized for oral absorption and intracellular delivery.

What it does. Glutathione neutralizes reactive oxygen species, regenerates other antioxidants, supports detoxification, and maintains cellular redox balance. Levels decline significantly with age.

Why we include it. Glutathione is the master regulator of cellular antioxidant defense. Replenishing it directly addresses the oxidative burden that accelerates biological aging.

What it is. Oleuropein is the primary bioactive polyphenol in olive leaves and oil — the compound most associated with the cardiovascular benefits of the Mediterranean diet.

What it does. Oleuropein supports healthy blood pressure, protects LDL from oxidation, and has demonstrated anti-inflammatory and autophagy-promoting effects in research settings.

Why we include it. Oleuropein brings Mediterranean diet longevity benefits in concentrated form — supporting cardiovascular health and cellular maintenance pathways.

What it is. PQQ is a redox cofactor that supports mitochondrial biogenesis — the creation of new mitochondria. It is one of the few compounds shown to increase mitochondrial number, not just function.

What it does. PQQ activates PGC-1α, the master regulator of mitochondrial biogenesis, stimulating cells to produce new mitochondria. It also provides potent antioxidant protection and supports cognitive function.

Why we include it. PQQ addresses mitochondrial decline not by supporting existing mitochondria, but by stimulating the creation of new ones — a unique and powerful longevity mechanism.

What it is. Quercetin is one of the most abundant flavonoids in the diet. Beyond its antioxidant properties, it has emerged as one of the most studied senolytic compounds.

What it does. Quercetin selectively induces apoptosis in senescent cells — damaged cells that have stopped dividing but resist normal cell death, accumulating with age and secreting inflammatory factors.

Why we include it. Quercetin's senolytic activity directly addresses one of the most important hallmarks of aging — the accumulation of senescent cells that drive inflammation and tissue dysfunction.

What it is. Zinc is an essential trace mineral required for over 300 enzymatic reactions, including those involved in DNA synthesis, immune function, and protein metabolism.

What it does. Zinc supports immune cell function, DNA repair mechanisms, and protein synthesis. Zinc deficiency accelerates with age and is associated with increased inflammation and impaired immune response.

Why we include it. Zinc addresses the age-related decline in immune function and DNA repair capacity — two systems critical for healthy longevity.

What it is. EPA is an omega-3 fatty acid with potent anti-inflammatory and cardioprotective properties. It is the precursor to specialized pro-resolving mediators that actively resolve inflammation.

What it does. EPA reduces systemic inflammation, supports cardiovascular health, and promotes the active resolution of inflammatory processes — addressing the chronic low-grade inflammation associated with aging.

Why we include it. EPA addresses "inflammaging" — the chronic inflammatory state that accelerates biological aging — through both anti-inflammatory and pro-resolving mechanisms.